Jennifer was recognized by the American Society for Biochemistry and Molecular Biology for excellence in research for her study of the HigBA toxin-antitoxin module. Jennifer did her Postdoctoral fellowship at the Geisel School of Medicine at Dartmouth with Drs. Jay Dunlap and Jennifer Loros, investigating the relationship between the core proteins and the output of the circadian clock in Neurospora. Her Fellowship was funded by the Ruth Kirschstein National Research Service Award from the National Institute of General Medical Sciences and she received a Perkins award for her contributions to Neurospora research. Jennifer joined the Department of Biological Sciences at Rensselaer Polytechnic Institute in 2015.
The brain's ability to clear a protein closely linked to Alzheimer's disease is tied to our circadian cycle, according to new research. The research underscores the importance of healthy sleep habits in preventing the protein Amyloid-Beta 42 (AB42) from forming clumps in the brain, and opens a path to potential Alzheimer's therapies.
Circadian regulation of immune cells plays a role in the intricate relationship between the circadian clock and Alzheimer's disease. This tells us a healthy sleep pattern might be important to alleviate some of the symptoms in Alzheimer's disease, and this beneficial effect might be imparted by an immune cell type called macrophages/microglia.